Pharma Intermediate

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Pharma Intermediate Manufacturer in India

As an expert pharma intermediate manufacturer in India, Advance Pharma Chem supplies high-purity intermediates used in API and formulation manufacturing. Our production processes follow strict quality standards, supported by in-house testing and technical expertise. We work closely with pharmaceutical companies to ensure reliable supply, batch-to-batch consistency, and scalable manufacturing for both commercial and custom requirements.

7-Chloroquinaldine

  • CAS Number: 4965-33-7
  • Molecular Formula: C10H8ClN
  • Molecular Weight: 177.63

Applications

1. It is used as a precursor in the preparation of MK-1 intermediate for Montelukast Sodium which is used as an immunosuppressant.
2. It is also used in the preparation of Quinophthalone dyes for plastics and LED’s

4-Nitro-1H-imidazole

  • CAS Number: 3034-38-6
  • Molecular Formula: C3H3N3O2
  • Molecular Weight: 113.07

Applications

1. It is used as an important intermediate for Anti TB drug Pretomanid which is a part of TB alliance drugs.
2. It is also used in the synthesis of anti-fungal drug Nimorazole.

2,5-Dibromo-4-nitro-1H-imidazole

  • CAS Number: 6154-30-9
  • Molecular Formula: C3HBr2N3O2
  • Molecular Weight: 270.87

Applications

1. It is used as an important intermediate for Anti TB drug Pretomanid which is a part of TB alliance drugs.

Isatin

  • CAS Number: 91-56-5
  • Molecular Formula: C8H5NO2
  • Molecular Weight: 147.13

Applications

1. It is used in the synthesis of Dibucaine/Cinchocaine for treatment as local anesthetic.
2. It is also used as an intermediate for the preparation of Solvent Yellow 114.
3. It has also shown promise as an intermediate to various anti-cancer and anti-retroviral drugs.

2-Hydroxy-1-naphthaldehyde

  • CAS Number: 708-06-5
  • Molecular Formula: C11H8O2
  • Molecular Weight: 172.18

Applications

1. Used as an intermediate for synthesis of Nafcillin antibiotic and Sirtinol.
2. It is also used in the synthesis of Pigment Yellow 101, Pigment Yellow 129, Pigment Orange 70, Solvent Violet 49, Solvent Red 212.

5-Bromo-2-chloropyrimidine

  • CAS Number: 32779-36-5
  • Molecular Formula: C4H2BrClN2
  • Molecular Weight: 193.43

Applications

1. It is used as an intermediate in the synthesis of Anti-hypertensive drug Aprocitentan and Macitentan.
2. It is also used as an intermediate in the synthesis of Lipid lowering drug Obicetrapib.

5-Chloro-2-nitrobenzoic acid

  • CAS Number: 2516-95-2
  • Molecular Formula: C7H4CINO4
  • Molecular Weight: 201.56

Applications

1. It is used in the synthesis of an important anti-coagulant drug Betrixaban.

5-Bromo-2-methylbenzoic acid

  • CAS Number: 79669-49-1
  • Molecular Formula:C8H7BrO2
  • Molecular Weight:215.4

Applications

1. It is used in the synthesis of anti-diabetic drug Canagliflozin.

2,6-Dichloro-3-cyano-4-methylpyridine

  • CAS Number: 875-35-4
  • Molecular Formula:C7H4Cl2N2
  • Molecular Weight:187.03

Applications

1. Used as an intermediate for the synthesis of Nevirapine which is an anti-HIV drug.
2. It is also used in the preparation of several specialty dyes intermediates.

4-Chloro-3-nitrobenzoic acid

  • CAS Number: 96-99-1
  • Molecular Formula:C7H4ClNO4
  • Molecular Weight:201.56

Applications

1. It is used in the synthesis of anti-fungal drug Mebendazole.
2. It is also used a precursor to antiviral drug Nintedanib.
3. It is also used in the synthesis of several specialty dyes and pigment intermediates.

2-Nitrobenzenesulphonyl chloride

  • CAS Number: 1694-92-4
  • Molecular Formula: C6H4CINO4S
  • Molecular Weight: 221.62

Applications

1. It is used an intermediate in the synthesis of drugs like Evocalcet, Ripasudil, Relebactum.

4-Bromobutyric acid

  • CAS Number: 2623-87-2
  • Molecular Formula: C4H7BrO2
  • Molecular Weight:167.00

Applications

1. It is also used as an intermediate in the synthesis of Lipid lowering drug Obicetrapib.
2. It is used in the synthesis of thrombolytic drug Ridogrel.

2-Chloro-5-nitrobenzoic acid

  • CAS Number: 2516-96-3
  • Molecular Formula: C7H4NO4
  • Molecular Weight: 201.56

Applications

1. It is an important intermediate in the synthesis of Mesalamine used to treat inflammatory bowel disease.

5-Bromo-2-chloro-N- cyclopentylpyrimidin-4-amine

  • CAS Number: 733039-20-8
  • Molecular Formula: C9H11BrClN3

Applications

1.It is used as an intermediate for anti-cancer API’s Palbociclib and Ribociclib

Chloroacetone

  • CAS Number: 78-95-5
  • Molecular Formula: C3H5CIO

Applications

1.It is used as a precursor in the synthesis of drugs like Lorlatinib, Ofloxacin and Promethazine etc.

5-Nitro salicylaldehyde

  • CAS Number: 97-51-8
  • Molecular Formula: C7H5NO4

Applications

1.It is used as a precursor in the synthesis of drugs like Pacritinib and Asenapine

Chloromethyl methyl ether

  • CAS Number: 107-30-2
  • Molecular Formula: C2H5CIO

Applications

1.It is used as a precursor in the synthesis of Pretomanid anti TB API.

2.It is also used as a precursor to various API’s like Troglitazone, Oseltamivir, Cefoxitin etc.

3.It is also used for the manufacture of certain Lubricants and agrochemicals.

4-Chloropyrrolo[2,3-d]-pyrimidine

  • CAS Number: 3680-69-1
  • Molecular Formula: C6H4ClN3

Applications

1.It is an important precursor to several anti-viral drugs such as Baciritinib, Tofacitinib, Itacitinib etc

2.It is also used as an intermediate for veterinary drugs such as Oclacitinib

2,4-Dichloropyrimidine

  • CAS Number: 3934-20-1
  • Molecular Formula: C4H2Cl2N2

Applications

1.It is an important precursor to Anti-neoplastic drugs such as Ribociclib, Mizolastine, Dapivirine, Merelitinib etc