Pharma Intermediate

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7-Chloroquinaldine

  • CAS Number: 4965-33-7
  • Molecular Formula: C10H8ClN
  • Molecular Weight: 177.63

Applications

1. It is used as a precursor in the preparation of MK-1 intermediate for Montelukast Sodium which is used as an immunosuppressant.
2. It is also used in the preparation of Quinophthalone dyes for plastics and LED’s

4-Nitro-1H-imidazole

  • CAS Number: 3034-38-6
  • Molecular Formula: C3H3N3O2
  • Molecular Weight: 113.07

Applications

1. It is used as an important intermediate for Anti TB drug Pretomanid which is a part of TB alliance drugs.
2. It is also used in the synthesis of anti-fungal drug Nimorazole.

2,5-Dibromo-4-nitro-1H-imidazole

  • CAS Number: 6154-30-9
  • Molecular Formula: C3HBr2N3O2
  • Molecular Weight: 270.87

Applications

1. It is used as an important intermediate for Anti TB drug Pretomanid which is a part of TB alliance drugs.

Isatin

  • CAS Number: 91-56-5
  • Molecular Formula: C8H5NO2
  • Molecular Weight: 147.13

Applications

1. It is used in the synthesis of Dibucaine/Cinchocaine for treatment as local anesthetic.
2. It is also used as an intermediate for the preparation of Solvent Yellow 114.
3. It has also shown promise as an intermediate to various anti-cancer and anti-retroviral drugs.

2-Hydroxy-1-naphthaldehyde

  • CAS Number: 708-06-5
  • Molecular Formula: C11H8O2
  • Molecular Weight: 172.18

Applications

1. Used as an intermediate for synthesis of Nafcillin antibiotic and Sirtinol.
2. It is also used in the synthesis of Pigment Yellow 101, Pigment Yellow 129, Pigment Orange 70, Solvent Violet 49, Solvent Red 212.

5-Bromo-2-chloropyrimidine

  • CAS Number: 32779-36-5
  • Molecular Formula: C4H2BrClN2
  • Molecular Weight: 193.43

Applications

1. It is used as an intermediate in the synthesis of Anti-hypertensive drug Aprocitentan and Macitentan.
2. It is also used as an intermediate in the synthesis of Lipid lowering drug Obicetrapib.

5-Chloro-2-nitrobenzoic acid

  • CAS Number: 2516-95-2
  • Molecular Formula: C7H4CINO4
  • Molecular Weight: 201.56

Applications

1. It is used in the synthesis of an important anti-coagulant drug Betrixaban.

5-Bromo-2-methylbenzoic acid

  • CAS Number: 79669-49-1
  • Molecular Formula:C8H7BrO2
  • Molecular Weight:215.4

Applications

1. It is used in the synthesis of anti-diabetic drug Canagliflozin.

2,6-Dichloro-3-cyano-4-methylpyridine

  • CAS Number: 875-35-4
  • Molecular Formula:C7H4Cl2N2
  • Molecular Weight:187.03

Applications

1. Used as an intermediate for the synthesis of Nevirapine which is an anti-HIV drug.
2. It is also used in the preparation of several specialty dyes intermediates.

4-Chloro-3-nitrobenzoic acid

  • CAS Number: 96-99-1
  • Molecular Formula:C7H4ClNO4
  • Molecular Weight:201.56

Applications

1. It is used in the synthesis of anti-fungal drug Mebendazole.
2. It is also used a precursor to antiviral drug Nintedanib.
3. It is also used in the synthesis of several specialty dyes and pigment intermediates.

2-Nitrobenzenesulphonyl chloride

  • CAS Number: 1694-92-4
  • Molecular Formula: C6H4CINO4S
  • Molecular Weight: 221.62

Applications

1. It is used an intermediate in the synthesis of drugs like Evocalcet, Ripasudil, Relebactum.

4-Bromobutyric acid

  • CAS Number: 2623-87-2
  • Molecular Formula: C4H7BrO2
  • Molecular Weight:167.00

Applications

1. It is also used as an intermediate in the synthesis of Lipid lowering drug Obicetrapib.
2. It is used in the synthesis of thrombolytic drug Ridogrel.

2-Chloro-5-nitrobenzoic acid

  • CAS Number: 2516-96-3
  • Molecular Formula: C7H4NO4
  • Molecular Weight: 201.56

Applications

1. It is an important intermediate in the synthesis of Mesalamine used to treat inflammatory bowel disease.